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Image Search Results
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience
Article Title: Synergistic effects of long-term antioxidant diet and behavioral enrichment on beta-amyloid load and non-amyloidogenic processing in aged canines
doi: 10.1523/JNEUROSCI.6194-09.2010
Figure Lengend Snippet: (A) Representative samples from the canine parietal cortex show the anti-oligomer A11 antibody detecting the Aβ oligomeric protein at 56kDa. (B) Lower levels and reduced variability of the 56kDa aggregate are seen in the combination treatment group EA despite a large amount of variability within the groups. (CC=control environment/control diet, EC=behavioral enrichment/control diet, CA=control environment/antioxidant diet, EA=behavioral enrichment/antioxidant diet, IP=immunoprecipitated canine sample with anti-Aβ1-16 6E10 antibody, numbers on left in A=kilodalton marker, kDa=kilodalton, OD=optical density; GAPDH=glyceraldehyde 3-phosphate dehydrogenase)
Article Snippet: The antibodies used in Western blots were β-actin (rabbit, 1:5000, Abcam Inc., Cambridge, MA), GAPDH (rabbit, 1:10,000; Chemicon, Temecula, CA), the N-terminal
Techniques: Immunoprecipitation, Marker